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Regulating intra-cellular communication via prostaglandins has revealed superior diurnal IOP treatments for all other glaucoma medical treatments. Coleus forskohlii also regulates intra-cellular communication via c-AMP which mediates most from the effects of prostaglandin PGE 2 (see chart).
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Significant improvement in visual fields indices were found after GBE treatment. Mean deviation (MD) at baseline was 17.40 +/- 3.27 dB versus 8.78 +/- 2.56 dB MD after GBE treatment; corrected pattern standard deviation (CPSD) at baseline was 10.93 +/- 2.12 dB versus eight.13 +/- 2.12 dB CPSD after GBE treatment. No significant changes were incorporated into intraocular pressure (IOP), blood pressure, or heart rate after placebo or GBE treatment. Research concluded that ginkgo biloba extract administration improves preexisting visual field damage in some patients with NTG.
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